Regeneration of a large bony lesion with advanced-platelet rich fibrin: Case Report

Ravi Gupta; Sagrika Shukla

doi:10.17126/joralres.2023.009

Ravi Gupta Department of Conservative Dentistry and Endodontics, Manipal University College Malaysia (MUCM), Jalan Batu Hampar, Bukit Baru, 75150 Melaka, Malaysia. http://orcid.org/0000-0002-1735-7247
Sagrika Shukla Shree Guru Gobind Singh Tricentenary University, dental college, Gurgaon, India. http://orcid.org/0000-0001-7751-3101

DOI: https://doi.org/10.17126/joralres.2023.009

Abstract

Introduction: This case report analyzes the regeneration potential of advanced-platelet rich fibrin (A-PRF) in large bony lesions. Advanced-platelet rich fibrin provides various growth factors which aids in faster healing.
Materials and Methods: Patient presented with peri-apical radiolucency. CBCT showed bony radiolucency in teeth 31, 32, 41, 42. A full mouth mucoperiosteal flap was raised and a cyst lining was enucleated. Apicoectomy was done with respect to 31, 32, 41, 42 along with and retrograde with a preparation of APRF clots were placed in the bony cavity.
Results: Post-op CBCT at 6 months showed a significant difference in size and bone density of the lesion.
Conclusions: Advanced-platelet rich fibrin has shown promising results in reducing the size of bony defect and periapical lesion in this case.
Keywords: Cysts; Apicoectomy; Endodoncia Regenerativa; Platelet-Rich Fibrin; Regeneration; Cone-Beam Computed Tomography.

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