Effectiveness of hyaluronic acid in the treatment of degenerative diseases of the temporomandibular joint: Literature Review.
Abstract
Objetive:The degenerative diseases of the tempo-romandibular joint (TMJ) are characterized by a progressive destruction of the articular tissues of the condyle and the glenoid fossa. The main aim of this review is to describe the effectiveness of the hyaluronic acid (HA) in the treatment of degenerative diseases of the TMJ in accordance with the available scientific evidence. Material and Methods: A literature search was made in the following databases EBSCO, Pubmed, Cochrane and Trip Database, using the keywords hyaluronic, hyaluronan, NaH, hyaluronate, TMJ, TMD, CMD, craniomandibular, orofacial pain and temporomandibular. There were no date or language restrictions applied. Results: After applying inclusion and exclusion criteria, 14 studies were included in this review (11 randomized controlled clinical trials and 3 non-randomized clinical trials). Conclusion: The studies reported a decrease in pain and improvement in functional parameters after treatment of TMJ osteoarthritis with HA. The use of arthrocentesis associated with the administration of HA provides effects synergistic, reaching a superiority the protocols with multiple injections with respect to those of a single session. The adverse effects related to the injection of HA with or without associated arthrocentesis were minor and transitory.
References
[1]. Peck CC, Goulet JP, Lobbezoo F, Schiffman EL, Alstergren P, Anderson GC, de Leeuw R, Jensen R, Michelotti A, Ohrbach R, Petersson A, List T. Expanding the taxonomy of the diagnostic criteria for temporomandibular disorders. J Oral Rehabil. 2014;41(1):2-23.
[2]. Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet J-P, et al. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Con-sortium Network and Orofacial Pain Special Interest Group. J Oral Facial Pain Headache. 2014;28(1):6-27.
[3]. Su N, Liu Y, Yang X, Shen J, Wang H. Correlation between oral health-related quality of life and clinical dysfunction index in patients with temporomandibular joint osteoarthritis. J Oral Sci. 2016;58(4):483-90.
[4]. Bag AK, Gaddikeri S, Singhal A, Hardin S, Tran BD, Medina JA, Curé JK. Imaging of the temporomandibular joint: An update. World J Radiol. 2014;6(8):567-82.
[5]. Dao TT, Lavigne GJ. Oral splints: the crutches for temporomandibular disorders and bruxism? Crit Rev Oral Biol Med Off Publ Am Assoc Oral Biol. 1998;9(3):345-61.
[6]. Türp JC, Komine F, Hugger A. Efficacy of stabilization splints for the management of patients with masticatory muscle pain: a qualitative systematic review. Clin Oral Investig. 2004;8(4):179-95.
[7]. Nitzan DW. ’Friction and adhesive forces’--possible underlying causes for temporomandibular joint internal derangement. Cells Tissues Organs. 2003;174(1-2):6-16.
[8]. Altman RD, Manjoo A, Fierlinger A, Niazi F, Nicholls M. The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review. BMC Musculoskelet Disord. 2015;16:321.
[9]. Machado E, Bonotto D, Cunali PA. Intra-articular injections with corticosteroids and sodium hyaluronate for treating temporomandibular joint disorders: a systematic review. Dent Press J Orthod. 2013;18(5):128-33.
[10]. Campos GC de, Rezende MU de, Pailo AF, Frucchi R, Pasqualim T, Camargo e OP de. Estudo prospectivo e randomizado que avalia a adição de corticoide à viscossuplementação: três meses de seguimento. Rev Bras Ortop. 2013;48(4):322-9.
[11]. Oxford Centre for Evidence-based Medicine - Levels of Evidence (March 2009). CEBM. 2009. Avalaible at: http://www.cebm.net/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/
[12]. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Int J Surg. 2010;8(5):336-41.
[13]. Des Jarlais DC, Lyles C, Crepaz N. Improving the Reporting Quality of Nonrandomized Evaluations of Behavioral and Public Health Interventions: The TREND Statement. Am J Public Health. 2004;94(3):361-6.
[14]. Assessing Risk of Bias in Included Studies, Cochrane Bias. Avalaible at: /bias/assessing-risk-bias-included-studies
[15]. Guarda-Nardini L, Masiero S, Marioni G. Conservative treatment of temporomandibular joint osteoarthrosis: intra-articular injection of sodium hyaluronate. J Oral Rehabil. 2005;32(10):729-34.
[16]. Bjørnland T, Gjaerum AA, Møystad A. Osteoarthritis of the temporomandibular joint: an evaluation of the effects and complications of corticosteroid injection compared with injection with sodium hyaluronate. J Oral Rehabil. 2007;34(8):583-9.
[17]. Guarda-Nardini L, Stifano M, Brombin C, Salmaso L, Manfredini D. A one-year case series of arthrocentesis with hyaluronic acid injections for temporomandibular joint osteoarthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(6):e14-22.
[18]. Møystad A, Mork-Knutsen BB, Bjørnland T. Injection of sodium hyaluronate compared to a corticosteroid in the treatment of patients with temporomandibular joint osteoarthritis: a CT evaluation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105(2):e53-60.
[19]. Manfredini D, Bonnini S, Arboretti R, Guarda-Nardini L. Temporomandibular joint osteoarthritis: an open label trial of 76 patients treated with arthrocentesis plus hyaluronic acid injections. Int J Oral Maxillofac Surg. 2009;38(8):827-34.
[20]. Tang YL, Zhu GQ, Hu L, Zheng M, Zhang JY, Shi ZD, Liang XH. Effects of intra-articular administration of sodium hyaluronate on plasminogen activator system in temporomandibular joints with osteoarthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(4):541-7.
[21]. Guarda-Nardini L, Cadorin C, Frizziero A, Ferronato G, Manfredini D. Comparison of 2 hyaluronic acid drugs for the treatment of temporomandibular joint osteoarthritis. J Oral Maxillofac Surg Off J Am Assoc Oral Maxillofac Surg. 2012;70(11):2522-30.
[22]. Manfredini D, Rancitelli D, Ferronato G, Guarda-Nardini L. Arthrocentesis with or without additional drugs in temporomandibular joint inflammatory-degenerative disease: comparison of six treatment protocols. J Oral Rehabil. 2012;39(4):245-51.
[23]. Guarda-Nardini L, Rossi A, Ramonda R, Punzi L, Ferronato G, Manfredini D. Effectiveness of treatment with visco-supplementation in temporomandibular joints with or without effusion. Int J Oral Maxillofac Surg. 2014;43(10):1218-23.
[24]. Guarda-Nardini L, Rossi A, Arboretti R, Bonnini S, Stellini E, Manfredini D. Single- or multiple-session viscosupplementation protocols for temporomandibular joint degenerative disorders: a randomized clinical trial. J Oral Rehabil. 2015;42(7):521-8.
[25]. Cömert Kiliç S, Güngörmüş M. Is arthrocentesis plus platelet-rich plasma superior to arthrocentesis plus hya-luronic acid for the treatment of temporomandibular joint osteoarthritis: a randomized clinical trial. Int J Oral Maxillofac Surg. 2016;45(12):1538-44.
[26]. Gurung T, Singh RK, Mohammad S, Pal US, Mahdi AA, Kumar M. Efficacy of arthrocentesis versus arthrocentesis with sodium hyaluronic acid in temporomandibular joint osteoarthritis: A comparison. Natl J Maxillofac Surg. 2017;8(1):41-9.
[27]. Alpaslan GH, Alpaslan C. Efficacy of temporomandibular joint arthrocentesis with and without injection of sodium hyaluronate in treatment of internal derangements. J Oral Maxillofac Surg Off J Am Assoc Oral Maxillofac Surg. 2001;59(6):613-8.
[28]. Guarda-Nardini L, Tito R, Staffieri A, Beltrame A. Treatment of patients with arthrosis of the temporomandibular joint by infiltration of sodium hyaluronate: a preliminary study. Eur Arch Oto-Rhino-Laryngol Off J Eur Fed Oto-Rhino-Laryngol Soc EUFOS Affil Ger Soc Oto-Rhino-Laryngol - Head Neck Surg. 2002;259(5):279-84.
[29]. Gokçe Kutuk S, Gökçe G, Arslan M, Özkan Y, Kütük M, Kursat Arikan O. Clinical and Radiological Comparison of Effects of Platelet-Rich Plasma, Hyaluronic Acid, and Corticosteroid Injections on Temporomandibular Joint Osteoarthritis. J Craniofac Surg. 2019;30(4):1144‐8.
[30]. Bergstrand S, Ingstad HK, Møystad A, Bjørnland T. Long-term effectiveness of arthrocentesis with and without hyaluronic acid injection for treatment of temporoman- dibular joint osteoarthritis. J Oral Sci. 2019;61:82–8.
[2]. Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet J-P, et al. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Con-sortium Network and Orofacial Pain Special Interest Group. J Oral Facial Pain Headache. 2014;28(1):6-27.
[3]. Su N, Liu Y, Yang X, Shen J, Wang H. Correlation between oral health-related quality of life and clinical dysfunction index in patients with temporomandibular joint osteoarthritis. J Oral Sci. 2016;58(4):483-90.
[4]. Bag AK, Gaddikeri S, Singhal A, Hardin S, Tran BD, Medina JA, Curé JK. Imaging of the temporomandibular joint: An update. World J Radiol. 2014;6(8):567-82.
[5]. Dao TT, Lavigne GJ. Oral splints: the crutches for temporomandibular disorders and bruxism? Crit Rev Oral Biol Med Off Publ Am Assoc Oral Biol. 1998;9(3):345-61.
[6]. Türp JC, Komine F, Hugger A. Efficacy of stabilization splints for the management of patients with masticatory muscle pain: a qualitative systematic review. Clin Oral Investig. 2004;8(4):179-95.
[7]. Nitzan DW. ’Friction and adhesive forces’--possible underlying causes for temporomandibular joint internal derangement. Cells Tissues Organs. 2003;174(1-2):6-16.
[8]. Altman RD, Manjoo A, Fierlinger A, Niazi F, Nicholls M. The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review. BMC Musculoskelet Disord. 2015;16:321.
[9]. Machado E, Bonotto D, Cunali PA. Intra-articular injections with corticosteroids and sodium hyaluronate for treating temporomandibular joint disorders: a systematic review. Dent Press J Orthod. 2013;18(5):128-33.
[10]. Campos GC de, Rezende MU de, Pailo AF, Frucchi R, Pasqualim T, Camargo e OP de. Estudo prospectivo e randomizado que avalia a adição de corticoide à viscossuplementação: três meses de seguimento. Rev Bras Ortop. 2013;48(4):322-9.
[11]. Oxford Centre for Evidence-based Medicine - Levels of Evidence (March 2009). CEBM. 2009. Avalaible at: http://www.cebm.net/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/
[12]. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Int J Surg. 2010;8(5):336-41.
[13]. Des Jarlais DC, Lyles C, Crepaz N. Improving the Reporting Quality of Nonrandomized Evaluations of Behavioral and Public Health Interventions: The TREND Statement. Am J Public Health. 2004;94(3):361-6.
[14]. Assessing Risk of Bias in Included Studies, Cochrane Bias. Avalaible at: /bias/assessing-risk-bias-included-studies
[15]. Guarda-Nardini L, Masiero S, Marioni G. Conservative treatment of temporomandibular joint osteoarthrosis: intra-articular injection of sodium hyaluronate. J Oral Rehabil. 2005;32(10):729-34.
[16]. Bjørnland T, Gjaerum AA, Møystad A. Osteoarthritis of the temporomandibular joint: an evaluation of the effects and complications of corticosteroid injection compared with injection with sodium hyaluronate. J Oral Rehabil. 2007;34(8):583-9.
[17]. Guarda-Nardini L, Stifano M, Brombin C, Salmaso L, Manfredini D. A one-year case series of arthrocentesis with hyaluronic acid injections for temporomandibular joint osteoarthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(6):e14-22.
[18]. Møystad A, Mork-Knutsen BB, Bjørnland T. Injection of sodium hyaluronate compared to a corticosteroid in the treatment of patients with temporomandibular joint osteoarthritis: a CT evaluation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105(2):e53-60.
[19]. Manfredini D, Bonnini S, Arboretti R, Guarda-Nardini L. Temporomandibular joint osteoarthritis: an open label trial of 76 patients treated with arthrocentesis plus hyaluronic acid injections. Int J Oral Maxillofac Surg. 2009;38(8):827-34.
[20]. Tang YL, Zhu GQ, Hu L, Zheng M, Zhang JY, Shi ZD, Liang XH. Effects of intra-articular administration of sodium hyaluronate on plasminogen activator system in temporomandibular joints with osteoarthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(4):541-7.
[21]. Guarda-Nardini L, Cadorin C, Frizziero A, Ferronato G, Manfredini D. Comparison of 2 hyaluronic acid drugs for the treatment of temporomandibular joint osteoarthritis. J Oral Maxillofac Surg Off J Am Assoc Oral Maxillofac Surg. 2012;70(11):2522-30.
[22]. Manfredini D, Rancitelli D, Ferronato G, Guarda-Nardini L. Arthrocentesis with or without additional drugs in temporomandibular joint inflammatory-degenerative disease: comparison of six treatment protocols. J Oral Rehabil. 2012;39(4):245-51.
[23]. Guarda-Nardini L, Rossi A, Ramonda R, Punzi L, Ferronato G, Manfredini D. Effectiveness of treatment with visco-supplementation in temporomandibular joints with or without effusion. Int J Oral Maxillofac Surg. 2014;43(10):1218-23.
[24]. Guarda-Nardini L, Rossi A, Arboretti R, Bonnini S, Stellini E, Manfredini D. Single- or multiple-session viscosupplementation protocols for temporomandibular joint degenerative disorders: a randomized clinical trial. J Oral Rehabil. 2015;42(7):521-8.
[25]. Cömert Kiliç S, Güngörmüş M. Is arthrocentesis plus platelet-rich plasma superior to arthrocentesis plus hya-luronic acid for the treatment of temporomandibular joint osteoarthritis: a randomized clinical trial. Int J Oral Maxillofac Surg. 2016;45(12):1538-44.
[26]. Gurung T, Singh RK, Mohammad S, Pal US, Mahdi AA, Kumar M. Efficacy of arthrocentesis versus arthrocentesis with sodium hyaluronic acid in temporomandibular joint osteoarthritis: A comparison. Natl J Maxillofac Surg. 2017;8(1):41-9.
[27]. Alpaslan GH, Alpaslan C. Efficacy of temporomandibular joint arthrocentesis with and without injection of sodium hyaluronate in treatment of internal derangements. J Oral Maxillofac Surg Off J Am Assoc Oral Maxillofac Surg. 2001;59(6):613-8.
[28]. Guarda-Nardini L, Tito R, Staffieri A, Beltrame A. Treatment of patients with arthrosis of the temporomandibular joint by infiltration of sodium hyaluronate: a preliminary study. Eur Arch Oto-Rhino-Laryngol Off J Eur Fed Oto-Rhino-Laryngol Soc EUFOS Affil Ger Soc Oto-Rhino-Laryngol - Head Neck Surg. 2002;259(5):279-84.
[29]. Gokçe Kutuk S, Gökçe G, Arslan M, Özkan Y, Kütük M, Kursat Arikan O. Clinical and Radiological Comparison of Effects of Platelet-Rich Plasma, Hyaluronic Acid, and Corticosteroid Injections on Temporomandibular Joint Osteoarthritis. J Craniofac Surg. 2019;30(4):1144‐8.
[30]. Bergstrand S, Ingstad HK, Møystad A, Bjørnland T. Long-term effectiveness of arthrocentesis with and without hyaluronic acid injection for treatment of temporoman- dibular joint osteoarthritis. J Oral Sci. 2019;61:82–8.
Published
2021-04-30
How to Cite
FERNANDEZ-VIAL, Diego; SILVA-ARCE, Fernando; RENNER, Nicole.
Effectiveness of hyaluronic acid in the treatment of degenerative diseases of the temporomandibular joint: Literature Review..
Journal of Oral Research, [S.l.], v. 10, n. 2, p. 1-10, apr. 2021.
ISSN 0719-2479.
Available at: <https://joralres.com/index.php/JOralRes/article/view/joralres.2021.008>. Date accessed: 16 apr. 2024.
doi: https://doi.org/10.17126/joralres.2021.008.
Issue
Section
Reviews
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. © 2024.
