Procalcitonin Levels In Individuals With Or Without Type 2 Diabetes Mellitus- A Cross-Sectional Study In Stage II Periodontitis Patients
Abstract
Aim: The objective of this current study is to evaluate and compare the concentrations of Procalcitonin (ProCT) in both serum and gingival crevicular fluid (GCF) of individuals with and without controlled Type II Diabetes Mellitus in relation to periodontal health and disease
Materials and Methods: In this study, 40 subjects were divided into four groups: 10 individuals with gingival health (Group 1), 10 with Type II Diabetes Mellitus (Group 2), 10 with Stage 2 Periodontitis and Type II Diabetes Mellitus (Group 3), and 10 with Stage 2 Periodontitis (Group 4). Baseline periodontal parameters such as gingival index, probing pocket depth, and clinical attachment level were recorded for each subject. Additionally, GCF and serum samples were collected, and ProCT levels were quantified using enzyme-linked immunosorbent assay (ELISA).
Results: Subjects with Stage 2 periodontitis and Type II Diabetes Mellitus were observed to have higher mean levels of GCF and serum ProCT compared to healthy patients and those with either periodontitis or diabetes mellitus alone. Additionally, ProCT levels were found to be higher in subjects with Type II Diabetes Mellitus compared to non-diabetics. Serum ProCT levels were also found to be higher than GCF levels.
Conclusion: The majority of edentulous patients both before and after prosthodontic rehabilitation had a lower calorie intake than recommended. There was no significant difference between calorie intake and physical status of patients after prosthodontic rehabilitation.
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