https://joralres.com/ojs-3.1.0/index.php/JOralRes/issue/feedJournal of Oral Research2025-01-30T14:34:27+00:00Dr. Celia A. Lima.journal@joralres.comOpen Journal Systems<h1>Sobre la revista</h1> <p><strong>Journal of Oral Research</strong>, se publica cada dos meses, está dedicada a la difusión del conocimiento en ciencias bucales, incluyendo: cirugía, medicina oral y rehabilitación, cirugía craneofacial, odontología, dolor orofacial y trastornos motores, habla y deglución, trastornos y otras disciplinas afines.</p> <p><strong>Journal of Oral Research</strong> publica artículos de investigación originales y comunicaciones breves, revisiones sistemáticas, protocolos de estudio, hipótesis de investigación, informes de casos, comentarios y perspectivas.</p> <p>Esta indexado por <strong>Scopus, DOAJ, LILACS, Latindex </strong> (Directorio y Catálogo), <strong>Free Medical Journals, IMBIOMED, VHL Regional Portal, SAGE Journals, Citefactor, DIALNET, <span class="orangePart">JournalTOCs</span>, Index Copernicus, REBIUN, REDIB</strong> and <strong>Google Scholar</strong>. <strong>Journal of Oral Research</strong> es miembro de <strong>COPE</strong>. </p> <p><strong>Journal of Oral Research</strong> es la publicación oficial de la Facultad de Odontología, Universidad de Concepción, Chile.</p> <p>ISSN Print 0719-2460 e ISSN Online 0719-2479.</p>https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.002Comparison of dental dimensions in models developed with digital procedures and plaster models2024-03-15T14:35:28+00:00Hooman Shafaeerangrazir@mums.ac.irFahimeh Farzaneganrangrazir@mums.ac.irBahareh Yaloodbardanrangrazir@mums.ac.irSeyed Hosein Hoseini Zarchrangrazir@mums.ac.irAbdolrasoul Rangrazirangrazir@mums.ac.ir<p><strong>Aim:</strong> This study aimed to collect evidence on the validity and reliability of measurements obtained from digital impression techniques. <br><strong>Materials and Methods:</strong> This comparative study was conducted on 31 patients. Intraoral scanner was applied to all patients. For each patient, an alginate impression of the upper maxilla was taken and later the 3D digital model was extracted by dental cone-beam computed tomography (CBCT). For preparation of plaster models, alginate impressions were taken and immediately poured with dental stone. In the next stage, a comparison was performed among the intraoral scanner, CBCT, and plaster models in terms of tooth size, dental width, and intra-arch dimensions. <br><strong>Results:</strong> Measuring tooth size and intra-arch dimensions in digital images obtained from intraoral scanner and CBCT were in most cases lower than the results obtained in the plaster models but the differences between digital techniques and plaster models are not clinically noticeable. <br>Conclusions: Digital systems including intraoral scanner and CBCT are acceptable for clinical use in terms of accuracy. <br><strong>Keywords:</strong> <em>Cone Beam Computed Tomography; Intraoral scanning; Plaster casts; Alginates; Orthodontics; Methods.</em></p>2024-03-15T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.003A feasible in vitro method to evaluate bacterial infiltration in three implant-abutment connection systems2024-05-09T00:38:12+00:00Alexandre Cavalcante de Queirozibsuffredini@yahoo.com.brIvana Barbosa Suffrediniibsuffredini@yahoo.com.brJosé Dimas de Oliveiraibsuffredini@yahoo.com.brJefferson de Souza Silvaibsuffredini@yahoo.com.brEduardo Fernandes Bondanibsuffredini@yahoo.com.br<p><strong>Introduction:</strong> Microorganism infiltration through the im-plant-abutment interface causes oral health problems such as periimplantitis, leading to implant loss. <br><strong>Materials and Methods:</strong> A feasible new method to quantify the <em>Streptococcus mutans (S. mutans)</em> infiltration through the implant-abutment interface gap is introduced in the present work. Internal hexagon (IH; n = 10), external hexagon (EH; n = 10), Morse taper (MT; n = 10), and a control for each group (n = 1) were tested. Bacteria suspension was prepared at 1.5x108 CFU/mL (CFU: colony forming units), and the implants were individually submerged up to the connection level, allowing the bacteria to contact it. The abutment was removed, and bacteria count was performed. <br><strong>Results:</strong> The implant sets were tested under normal bacterial growth and early and late biofilm growth conditions. Colony-forming units per mL were obtained, and the results were compared among groups. Differences in bacterial count between the MT and EH (<em>p</em><0.001) and the MT and IH (p<0.001) groups were significantly higher in the MT-type implant. There was a significant increment of bacterial infiltration in the MTs submitted to late biofilm growth conditions. EH and IH connections are more effective in preventing bacterial infiltration independent of the growth condition. <br><strong>Conclusions:</strong> The proposed methodology is feasible to evaluate the infiltration of microorganisms through the implant-abutment interface.<br><strong>Keywords:</strong> <em>Biofilm; Bacteria; infiltration; Streptococcus mutans; Dental implants; In vitro techniques.</em></p>2024-03-31T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.004Evaluation of the root morphology of mandibular first premolars using cone-beam computed tomography in a peruvian population2024-07-08T20:57:05+00:00Olger Benavides-Guzmanluchoarriola@gmail.comYalil Rodríguez-Cárdenasluchoarriola@gmail.comAron Aliaga-del Castilloluchoarriola@gmail.comGustavo Armando Ruíz-Moraluchoarriola@gmail.comLuis Ernesto Arriola-Guillénluchoarriola@gmail.com<p><strong>Introduction:</strong> The morphology of the root canal of the first premolars is not always the same and therefore a good knowledge of its dental anatomy is essential. <br><strong>Aim:</strong> To assess the morphology of roots and root canals of mandibular first premolars in a Peruvian population using cone-beam computed tomography (CBCT).<br><strong>Materials and Methods:</strong> This was a descriptive cross-sec-tional study. A total of 370 mandibular first premolars fulfilling the inclusion criteria were evaluated using CBCT, and the number of roots and root canals, the Vertucci’s classification of root canal configuration, age, sex and side of the tooth were registered. <br><strong>Results:</strong> One and two roots were presented in 96.2% (n=356) and 3.8% (n=14), respectively, of the mandibular first premolars analyzed, and one canal was present in 67.6% (n=250) and two canals in 32.2% (n=119). A type I root canal configuration was found in 67.6% (n=250) of the cases followed by type V with 26.2% (n=97). A statistically significant association was found between the number of roots and canals (<em>p</em><0.001) and age also had a significant influence on this variable (<em>p</em>=0.0043).<br><strong>Conclusions:</strong> The presence of one canal in mandibular first premolars is the most frequent, although there is a considerable prevalence of two in the population studied. The number of roots is associated with the number of canals, with age having a significant influence on these variables.<br><strong>Keywords:</strong> <em>Cone-Beam Computed Tomography; Mandibular first premolar; Vertucci Configuration; Anatomy, Radiology .</em></p>2024-05-10T14:42:39+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.005Comparative evaluation of hydrogen peroxide and Chlorhexidine mouthwash on salivary interleukin-1ß levels in patients with type 2 diabetes mellitus and chronic periodontitis: a randomized controlled clinical trial2024-04-15T14:40:20+00:00Swet Nishaswetnisha1@gmail.comDebanjan Dasswetnisha1@gmail.comSandip Kulaviswetnisha1@gmail.comPratibha Shashikumarswetnisha1@gmail.com<p><strong>Introduction:</strong> Periodontal inflammation causes dysbiosis and change in the microbiota. Nonsurgical periodontal therapy (NSPT) helps in removal of plaque and restoring periodontal health. Various adjunctive therapy like use of mouthwash helps in maintenance of periodontal health and reducing inflammatory load.<br><strong>Materials and Methods:</strong> A total of 108 subjects diagnosed with type 2 diabetes mellitus and periodontitis were divided into three groups: Group 1 received NSPT and rinsing with 0.2% chlorhexidine mouthwash for 3 months, Group 2 received NSPT and rinsing with 1.5% hydrogen peroxide mouthwash for 3 months, Group 3- received NSPT only (control group). The clinical parameters measured included Plaque Index (PI), Gingival Index (GI), Bleeding on probing (BOP) and probing (PD) at baseline, 1, 2, 3 months follow up. Salivary interleukin 1βlevels were measured at baseline and 3 months interval.<br><strong>Results: </strong>Group 1, 2 and 3 showed significant reduction in PI, GI, BOP and PD at 1 and 3 months follow up (<em>p</em><0.05). However, Intergroup comparison of clinical parameters showed significant reduction in group 1 and 2 when compared with group 3 (<em>p</em><0.05). Salivary interleukin 1-β levels showed significant reduction from baseline to 3 months in all the three groups and intergroup comparison didn’t show any significant changes, (<em>p</em>>0.05).<br><strong>Conclusions:</strong> Hydrogen peroxide mouthwash as an adjunct to NSPT can be considered as a safe and effective measure to reduce periodontal inflammation in type 2 diabetes mellitus patients with chronic periodontitis.<br><strong>Keywords:</strong> <em>Chlorhexidine; Hydrogen peroxide; Mouthwashes; Periodontitis; ultrasonics; dental scaling.</em></p>2024-04-01T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.008Analysis of primary caregivers’ knowledge concerning the cariogenic risk associated with the use of pediatric liquid medications2024-07-09T15:23:35+00:00Florencia Cáceres-Riverosf.caceresr97@gmail.comPaula Karin-Naveaf.caceresr97@gmail.comNicolás Dufey-Portillaf.caceresr97@gmail.comCristina Barrera-Gutierrézf.caceresr97@gmail.comJaviera Brantt-Branttf.caceresr97@gmail.com<p><strong>Introduction:</strong> Pediatric liquid medications (PLM) are frequently administered to children, yet their usage may contribute to the onset of dental caries. Despite its prevalence, there is a notable scarcity of scientific research regarding caregivers’ knowledge of this potential cariogenic risk.<br><strong>Objective:</strong> This study aims to assess the knowledge of the main caregivers of children aged 5 to 12 years concerning the cariogenic potential associated with the use of PLM.<br><strong>Materials and Methods:</strong> A cross-sectional analytical obser-vational study involving 152 primary caregivers of children aged 5 to 12 was conducted. Data were collected on caregivers’ perceptions of the cariogenic risk associated with PLMs and their consumption habits. The study also assessed oral hygiene routines and evaluated the level of information provided by healthcare professionals.<br><strong>Results:</strong> Research findings indicated a significant lack of awa-reness among primary caregivers regarding the cariogenic risks of PLMs, with 78.95% being unaware of these risks and 47.37% unaware of the sugars present in such medications. Additionally, a high rate of PLM consumption was observed, with 63% of caregivers using them in the last year. The study underscored a notable absence of guidance from healthcare professionals, as 91.45% of the caregivers stated that they had not received instructions on tooth brushing after the administration of the PLM.<br><strong>Conclusions:</strong> The study highlights a significant lack of awa-reness among primary caregivers regarding the cariogenic risks associated with the ingestion of pediatric liquid medications. This deficit in information and preventive measures presents a substantial obstacle to children’s oral health. To address this issue, it is crucial for healthcare professionals to offer comprehensive guidance and promote preventive measures.<br><strong>Keywords:</strong> <em>Dental Caries; Knowledge; Caregivers; Child; Pharmaceutical Preparations; Oral hygiene.</em></p>2024-06-04T16:10:20+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.009Effects of furcation involvement on molar survival in periodontally treated patients2024-07-09T15:34:46+00:00Nurul Ain Mohamed Yusofnurul4inmy@gmail.comMohd Azri Mohd Suannurul4inmy@gmail.comRusmizan Yahayanurul4inmy@gmail.com<p><strong>Objective:</strong> This study aims to analyze the survival time of molar tooth according to furcation involvement (FI) classification among periodontally treated patients under a supportive periodontal care program.<br><strong>Materials and Methods:</strong> A retrospective study was con-ducted among 77 periodontitis patients with 240 molars who had undergone periodontal therapy that were followed up with supportive periodontal therapy (SPT) for at least five years. Periodontitis patients’ data were retrieved from the periodontic clinical record. The clinical parameters of all involved molars and treatment modality were recorded at baseline and SPT.<br><strong>Results:</strong> A total of 69 (28.8%) molars were extracted during active periodontal therapy, while 17 (7.1%) were lost during SPT. The 5-year survival rate of molars was 83.5% (95% confidence interval [CI], 76.9-88.4) for FI=0 (n=141), 81.0% (95% CI, 56.9-92.4) for FI=I (n=18), 50.0% (95% CI, 33.8-64.2) for FI=II (n=21), and 25.0% (95% CI, 6.9-48.8) for FI=III (n=4). Additionally, the 10-year survival rate for molars with FI = III was 12.5% (95% CI, 1.0-39.2), which was lower than that of molars with FI = 0 (77.1%; 95% CI, 69.7-83.0).<br><strong>Conclusions:</strong> The presence of a high degree of FI classifica-tion, especially Class III, is associated with a lower survival rate of molars among periodontally treated patients. Retention of molars is possible on a long-term basis through a maintenance program of periodontal therapy.<br><strong>Keywords:</strong> <em>Furcation defects; Molar; Periodontitis; Survival rate; Tooth loss; Clinical Record.</em></p>2024-06-05T15:02:54+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.010Association between early childhood caries and nutritional status in children in a Peruvian social program. A cross-sectional study2024-06-05T16:30:08+00:00Tania Padilla-Cácerestpadilla@unap.edu.peVilma Mamani-Coritpadilla@unap.edu.peLuz Caballero-Apazatpadilla@unap.edu.peSheyla Cervantes-Alagóntpadilla@unap.edu.peHeber Arbildo-Vegatpadilla@unap.edu.pe<p><strong>Introduction:</strong> Early childhood caries is still very prevalent, mainly in developing countries, and it is related to the quality of life of children due to early tooth loss.<br><strong>Objective:</strong> The study objective was to determine the association between dental caries and its clinical consequences on nutritional status in children of the “<em>Vaso de Leche</em> (Glass of Milk)’’ social program, in Puno City, Peru, during the year 2020. <br><strong>Materials and Methods:</strong> An observational, descriptive-correlational, cross-sectional study; the sample consisted of 740 children between 1 and 5 years old who met the selection criteria; the clinical consequences of untreated dental caries were evaluated using the PUFA index and the prevalence of caries with def-t; the nutritional status was determined by the weight and height of the child according to protocols (NTS No. 357 - MINSA /2017/ DGIESP); the data were analyzed with the SPSS-v25 program, the association between variables was evaluated with the chi-square test, Mann-Whitney U test and Spearman’s Rho test, considering significance at a <em>p</em>-value <0.05.<br><strong>Results:</strong> No significant relationship was found when dental caries was evaluated with the nutritional condition (<em>p</em><0.05). However, when the def-t index values were related to the nutritional condition of the children, a significant difference was found (<em>p</em><0.05). There was no significant difference with the PUFA index (<em>p</em>>0.05). <br><strong>Conclusions:</strong> There is no association between early childhood caries and nutritional status in children aged between 3 and 5 years; however, a significant relationship was found between the values of the def-t index and the nutritional status of the children.<br><strong>Keywords:</strong> <em>Dental caries; Nutritional status; Overweight; Child, preschool; Thinness; Body Mass Index.</em></p>2024-06-05T15:20:47+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.011Assessment of attributes for choosing a dental center in Trujillo, Peru: patients versus dentists2024-05-29T16:25:34+00:00Karem Maytee Carranza-Fernándezaasmata1@upao.edu.peÁngel Steven Asmat-Abantoaasmata1@upao.edu.peRosita Elena Espejo-Carreraaasmata1@upao.edu.pe<p><strong>Objective:</strong> To determine the difference between patients and dentists regarding the assessment of attributes for choosing a dental center in Trujillo, Peru.<br><strong>Materials and Methods:</strong> A comparative cross-sectional observational study was conducted involving a sample of 162 dentists and 162 patients from the Trujillo province in Peru. The data was collected through a virtual questionnaire, validated by experts, and assessed for reliability. Statistical analysis was performed using the U-Mann Whitney and Spearman correlation tests, with a significance level set at 5%.<br><strong>Results:</strong> Patients, in comparison to dentists, demonstrated a greater preference for selecting a dental center where the practitioner is a recognized specialist (<em>p</em><0.001). Similarly, patients showed a preference for centers offering expedited appointments, advanced technology, and equipment, providing affordable and flexible payment options, free consultations, and having convenient parking and comfortable facilities (<em>p</em><0.05). Conversely, dentists perceived that the most valued attribute by patients is the recommendation of the dentist (<em>p</em>=0.031).<br><strong>Conclusions:</strong> When choosing a dental center, patients primarily value attributes related to both the professional responsible for care and administrative management. Conversely, dentists consider the main factor influencing a patient’s choice of dental center to be recommendations of the dentist. Valoración de los atributos para la elección de un centro odontológico en Trujillo, Perú: pacientes versus odontólogos<br><strong>Keywords:</strong> <em>Dentist-patient relations; Dental offices; Dental practice management; Health services administration; Biosecurity; Peru.</em></p>2024-05-29T16:20:24+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.012Effectiveness of commercially available denture adhesives on retention of mandibular complete denture in resorbed mandibular ridge: An in vitro study2024-07-08T22:02:36+00:00Indumathi Sivakumarcherub2008@gmail.comTanx Qing Wencherub2008@gmail.comSara Luay Thanooncherub2008@gmail.comShivanii Prabakarencherub2008@gmail.comTimothy Teo Yiicherub2008@gmail.comThanesh Sinnathambycherub2008@gmail.com<p><strong>Background:</strong> Denture adhesives are alternatives used to improve retention, stability, comfort and satisfaction in patients with complete dentures. Evidence on the effectiveness of denture adhesives on resorbed mandibular ridges is scarce. Among the many commercially available denture adhesives, the ideal material for the severely resorbed mandibular ridge remains in dispute. Objective: The aim of this study was to evaluate the effectiveness of different quantities of four commercially available denture adhesives on the retention of mandibular complete dentures in severely resorbed ridges.<br><strong>Materials and Methods:</strong> A resorbed edentulous mandibular ridge model was manufactured in acrylic resin. A denture base was made and three loops were attached to it. Four commercially available denture adhesives (Fixodent, Perlie White, Fiftydent and Polident) were tested in amounts of 0.2 g, 0.4 g, 0.6 g, 0.8 g and 1.0 g. The acrylic resin model was evenly moistened with 1 ml of water and a weighted amount of adhesive material was applied to the denture base. The universal testing machine engaged the loops fixed on the denture base and applied the vertical displacement force. The maximum vertical displacement force values were recorded for each denture adhesive material at different amounts. Statistical calculation was performed using Kruskal Wallis with Bonferroni post hoc correction.<br><strong>Results:</strong> Statistically significant differences were observed in the mean values of the vertical displacement force for adhesive amounts of 0.2 g, 0.4 g, 0.6 g and 1.0 g (<em>p</em><0.05) between the four adhesive materials tested. Statistically significant differences were observed when four denture adhesives were compared to each other in different amounts (<em>p</em><0.05). Statistically significant differences were observed between different amounts for each of four denture adhesives (<em>p</em><0.05).<br><strong>Conclusions:</strong> Among the four materials tested, Polident showed greater effectiveness at 0.6 g and 0.8 g, Fittydent at 0.6 g, 0.8 g and 1 g, Fixodent at 0.4 g and 0.6 g and Perlie White at 1 g and 0.8g quantity to resist vertical displacement. forces on the severely resorbed mandibular crest. Using an appropriate amount of denture adhesive allows for proper retention of the denture; Replacement of this adhesive is necessary once a day.<br><strong>Keywords:</strong> <em>Denture retention; Alveolar ridge; Mandible; Adhesives; Effectiveness; Denture, complete.</em></p>2024-06-06T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.013Nasolabial anthropometry using 3D computed tomography scan reconstruction: baseline study for nasolabial correction in Indonesian children with cleft lip and palate2024-07-09T16:11:15+00:00Erli Sarilitaerli.sarilita@fkg.unpad.ac.idHarry Galuh Nugrahaerli.sarilita@fkg.unpad.ac.idNani Murniatierli.sarilita@fkg.unpad.ac.idEndang Sjamsudinerli.sarilita@fkg.unpad.ac.idHarmas Yazid Yusuferli.sarilita@fkg.unpad.ac.id<p><strong>Background:</strong> The normal nasolabial structure of infants and chil-dren from East Asian, specifically Indonesian, descent groups has been less explored in the literature. This anthropometric study is used as a guide in lip repair in patients with clefts. This retrospective study used archived CT images from the Indonesian population.<br><strong>Materials and Methods:</strong> Computed tomography records of children under 5 years of age were extracted from a provincial hospital. The images were then filtered based on the inclusion and exclusion criteria and then the 2D slices were reconstructed using the open source software Invesalius. Twenty-five variable nasolabial parameters of the nasolabial structure were then measured in the 3D rendering mode. Images with craniofacial dysmorphism or cannulas that passed over the nasolabial structure were excluded. Results were summarized using descriptive statistics.<br><strong>Results:</strong> Fourteen of 128 CT images were included in this study. The samples were divided into two age groups: 0-12 months and 25-54 months. There were moderate to strong, positive correlations between age and all nasolabial variables, which were statistically significant (<em>p</em><0.05) except for nasal length, nares circumference, columella width, superior philtrum width, philtrum column height, and cutaneous upper lip height.<br><strong>Conclusions:</strong> This study described anthropometric measurements of normal nasolabial structures as a reference point for lip correction surgery. However, to obtain more accurate anthropometric guidelines, further studies with larger sample sizes are desirable. Although surgical repair of the lip is usually performed within the first year of life, some cases of surgery are performed after infancy.<br><strong>Keywords:</strong> <em>Indonesia; Anthropometry; Tomography; Cleft lip; Infant; Child, preschool.</em></p>2024-06-23T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.014Influence of different opacities and layering technique of nanotechnology composite resins regarding the wavelength and fluorescence intensity: in vitro study2024-07-08T22:07:24+00:00Carla Portocarrero-Florescarladaniela380@hotmail.comThais Alcandrécarladaniela380@hotmail.comAlberth Correa-Medinacarladaniela380@hotmail.com<p><strong>Objective:</strong> To evaluate the influence of opacity and the layering technique on the fluorescence of different composite resins. <br><strong>Materials and Methods:</strong> Two opacities (enamel and dentin) and the layering technique (enamel + dentin) of the composite resins: Filtek® Z350 and Palfique LX5 were evaluated in vitro. Composite resin discs were fabricated using a preformed matrix of 10 mm diameter and 0.5 mm thick for the single opacity groups and 10 mm thick for the layering technique groups, using 2 layers of 0.5 mm thickness of each opacity (n = 5). Specimens were analyzed using the Raman spectroscopy method. Data were analyzed using the Kruskall-wallis and Mann-Whitney U tests. <br><strong>Results:</strong> When evaluating the intensity of fluorescence, no statistically significant difference was found when comparing the layering technique and enamel opacity (<em>p</em>2> 0.05) and an increase in the dentin opacity value for both brands of composite resin. Regarding wavelength, no statistically significant difference was found when comparing the layering technique with enamel opacity and dentin opacity for both Filtek® Z350 and Palfique LX5® composite resins (<em>p</em>2 > 0.05).<br><strong>Conclusions:</strong> The fluorescence intensity of the layering technique is similar to enamel opacity for both composite resins. Likewise, the wavelength of the layering technique is similar to the enamel opacity and dentin opacity for both brands.<br><strong>Keywords:</strong> <em>Composite resins; Fluorescence; Spectrum analysis; Spectrum analysis, Raman; In vitro techniques; Nanotechnology.</em></p>2024-06-23T23:21:55+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.016Changes on food intake, body weight and salivary amylase synthesis in the submandibular gland of Wistar rats treated with Bevacizumab and cytostatics2024-07-08T23:12:17+00:00Claudio Gastón Dubersarskymarcelo.mazzeo@unc.edu.arEvelin Bachmeiermarcelo.mazzeo@unc.edu.arCatalina Melchora Franciamarcelo.mazzeo@unc.edu.arMaría Angélica Rivoiramarcelo.mazzeo@unc.edu.arDaniela Josefina Portamarcelo.mazzeo@unc.edu.arMabel Noemí Brunottomarcelo.mazzeo@unc.edu.arMarcelo Adrián Mazzeomarcelo.mazzeo@unc.edu.ar<p><strong>Background:</strong> Bevacizumab together with 5-fluorouracil and oxaliplatin inhibit microvascular growth of tumor blood vessels and tumor proliferation. Few reports state the effect of these therapeutic schemes on salivary glands. <br><strong>Materials and Methods:</strong> Food consumption, body weight and salivary amylase activity were assessed in the submandibular gland of rats. Adult male Wistar rats, of three months old with 350/400 grams body weight, under 12-hour light/dark cycles respectively, were divided into the following experimental groups: G1) Control group, G2) 5-Fluorouracil and leucovorin calcium treated group, G3) Bevacizumab treated group, G4) Oxaliplatin treated group, G5) Bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin calcium treated group and G6) Drug-free paired feeding treated group. Assessment of treatment effect was performed by one-way ANOVA. A value of p<0.05 was set for statistical significance. <br><strong>Results:</strong> Salivary amylase activity in gland homogenate was G1: 137.9 ± 4.64, G2: 60.95±4.64, G3: 120.93 ± 4.96, G4: 26.17 ±4.64, G5: 10.77 ±4.64 and G6: 82.87 ±4.64 U/mg protein (mean ± S.D.) Amylase activity in the G1 group was higher relative to the other experimental groups <em>p</em><0.0001. <br><strong>Conclusions:</strong> The drugs 5-fluorouracil and oxaliplatin altered salivary amylase activity by serous granules of the submandibular gland interpreted as a mechanism of impaired acinar function. Bevacizumab administered in isolation did not alter salivary amylase activity compared to the control group. While the lower intake of the matched feeding group affected salivary amylase activity compared to the control group, the effect was significantly greater in animals treated with the oncology drugs used in the present animal model.<br><strong>Keywords:</strong> <em>Chemotherapy; Antibodies, monoclonal; Dietary intake; Body weight; Amylase; Submandibular gland.</em></p>2024-07-08T22:25:37+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.017Effect of Adding Fluoride to Camellia sinensis Against Dentin Erosion Generated by Non-Bacterial Acids2024-07-25T15:30:43+00:00Ricardo Reyes-Mansilladramosp@unmsm.edu.peDonald Ramos-Perfectodramosp@unmsm.edu.peLuis Maita-Vélizdramosp@unmsm.edu.peEduardo López-Pagandramosp@unmsm.edu.peLuis Maita-Castañedadramosp@unmsm.edu.pe<p><strong>Introduction:</strong> Natural products are an option to be used in different conditions in the oral cavity, such as <em>Camellia sinensis</em>, which due to its different properties would be beneficial in the erosion of the dental surface. <br><strong>Objetive:</strong> Determinar el efecto del extracto de <em>Camellia sinensis (C. sinensis)</em> adicionado con flúor frente a la acción erosiva de ácidos no bacterianos en la superficie de la dentina humana<br><strong>Materials and Methods:</strong> Quasi-experimental, prospective, longitudinal, and<em> in vitro</em> study, consisting of 50 samples of human dentin, which were classified into 5 study groups: distilled water, hydrochloric acid, 2%<em> C. sinensis</em> extract, sodium fluoride. 2% and 2% <em>C. sinensis</em> extract added with 2% sodium fluoride. The surface roughness of each sample was evaluated with the SRT6200 digital roughness meter, obtaining a total average roughness and the measurements were carried out in two moments. <br><strong>Results:</strong> It was observed that the 2% <em>C. sinensis</em> extract, the 2% sodium fluoride, and the <em>C. sinensis</em> extract added with 2% sodium fluoride, showed a variation in surface roughness between before and after, which was not significant (<em>p</em><0.05) in all cases. It should be noted that the <em>C. sinensis</em> plus sodium fluoride group is the one that obtained the best variation in the mean surface roughness than the other groups studied. <br><strong>Conclusions:</strong> The 2% <em>C. sinensis</em> extract, 2% sodium fluoride, and the combination of both compounds demonstrated an inhibitory effect against the erosive action of hydrochloric acid (0.01 M) on the dentin surface, not presenting a statistically significant difference in the results.<br><strong>Keywords:</strong> <em>Camellia sinensis; Tooth erosion; Fluorides; Dentina; Surface properties; Prospective studies.</em></p>2024-07-25T15:14:11+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.020Characteristics of the Buccal Shelf for the installation of miniscrews in Chilean individuals aged 15-45 years: a descriptive study2024-10-28T14:52:45+00:00Lourdes Wanglourdes.wang@miuandes.clRodrigo Oyonartelourdes.wang@miuandes.clRaimundo Carmonalourdes.wang@miuandes.clCarolina Bidartlourdes.wang@miuandes.clGianfranco Battaglialourdes.wang@miuandes.cl<p><strong>Introduction:</strong> Orthodontic mini-screws allow complex therapeutic objectives to be achieved conservatively, so their use in clinical practice has increased considerably in recent years. The most important aspect to consider is the stability when installing it, related to the thickness of the cortical bone in the area where it is implanted. In the mandible, it has been seen that the area with the highest success rate is that of the buccal shelf (BS). Several studies have proposed variation in its location and bone thickness according to the characteristics of each patient. <strong>Objective:</strong> To describe the characteristics of the mandibular vestibular balcony (Buccal Shelf or BS) through the study of CBCT in individuals between 15-45 years of age in the Metropolitan Region of Santiago de Chile.<br><strong>Materials and Methods:</strong> Full-head CBCT images of 159 patients aged 15 to 45 years were analyzed, categorized into 3 groups classified according to age between 15-24 years; 25-34 years; 35-45 years. The patients’ facial pattern was measured based on Steiner’s S-N-Go-Gn angle, where it was classified into three ranges; less than 30 degrees, between 30 and 34 degrees, greater than 34 degrees and were analyzed with BlueSkyPlan software4. For the statistical tests, the normality in the distribution of the data was first analyzed through the Shapiro-Wilk test. For the comparison between variables, the Kruskal Wallis test was used with Bonferroni’s multiple comparisons test. The Horos v.3.3.5 program was used for measurements of alveolar cortical thickness and the angle formed by the cortical contour of the BS in relation to the axial axis of the respective molar. All images were obtained with a KODAK 9500 CT scanner and stored in DICOM files.<br><strong>Results:</strong> The distance from the cortical to the tooth root increases from mesial to distal and as depth increases. When assessing the distance from the cortical to the inferior alveolar nerve, it also increases from mesial to distal, but decreases as the depth of the site increases. The greatest distance is from the vestibular cortical of the distal site of the second mandibular molar at 7mm depth to the root of the same tooth and, also, the vestibular cortical of the distal site of the second mandibular molar at 5 mm depth to the alveolar nerve.<br><strong>Conclusion:</strong> From mesial to distal in this area, the slope of the vestibular balcony increases, becoming flatter; likewise, the distance to the molar root and mandibular alveolar nerve measured from the alveolar cortical also increases. This may be due to the principle of mandibular growth and physiological characteristics of the posterior mandibular area. Different facial patterns show differences in the anatomy of the vestibular balcony, mainly in the angle of the vestibular balcony, but not in the thickness of the alveolar cortical bone in this area. It is important to consider that the variations found in other studies may be due primarily to racial differences. <br><strong>Keywords:</strong> Mandibular vestibular shelf; Bone screws; Orthodontic anchorage procedures; Cortical bone; Mandible; Orthodontics.</p>2024-07-30T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/1599Analysis of root canal obturation length in endodontic treatments performed by undergraduate dental students2024-10-28T15:19:49+00:00Joaquín Lucero-Morajlucerom@uft.eduAlanis Galaz-Cabrerajlucerom@uft.eduAntonia Espinoza-Romerojlucerom@uft.edu<p><strong>Introduction: </strong>Cross-sectional observational study whose purpose was to analyze the length of root canal obturation, according to the Barrieshi-Nussair criteria, in endodontic treatments performed by undergraduate students at the School of Dentistry at Finis Terrae University, in the year 2022.<br><strong>Results:</strong> 88.5% obtained an acceptable obturation length, 6.7% were overfilled and 4.8% were underfilled. Regarding the academic year, in the 4<sup>th</sup> year, 77.8% of the endodontic treatments had an acceptable obturation length; in the 5th year, 89.4%; and in the 6<sup>th</sup> year, 90%. In the lower jaw, 89.3% were acceptable and in the upper jaw, 88.2% were acceptable. In the incisor group, 83.3% achieved an acceptable obturation length, 100% in the canines and 89.1% in the premolars.<br><strong>Conclusion:</strong> The results obtained in this study were superior to some described in the Middle East, lower or similar to those found in Europe, and comparable to others reported in Chile. In all variables, the percentage of acceptable obturation length according to the Barrieshi-Nusair criteria was predominant (77.8% for 4<sup>th</sup>, 89.4% for 5<sup>th</sup>, 90% for 6th, 89.3% for mandible, 88.2% for maxilla, 83.3% for incisors, 100% for canines and 89.1% for premolars). This high percentage of acceptable treatments may be due, among other factors, to the use of the electronic apical locator and the accompaniment of specialists during undergraduate training and endodontic treatment.<br><strong>Keywords:</strong><em> Dental students; Root canal therapy; Root canal preparation; Endodontics; Root canal filling materials; Root canal obturation</em></p>2024-10-28T15:19:49+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.001Phenotypic characteristics and differentiation potential of gingival mesenchymal stem cells in hyperglycemia — An ex vivo exploratory study2025-01-30T14:34:27+00:00Suman Basavarajudrveenahr@gmail.comMR Dhakshainidrveenahr@gmail.comAnshukumar Yadavdrveenahr@gmail.comHR Veenadrveenahr@gmail.comRiya Achamma Danieldrveenahr@gmail.com<p><strong>Background:</strong> The therapeutic use of gingival mesenchymal stem cells (GMSCs) as autologous cells may pose the challenge of alterations inflicted by the hyperglycemic environment. <br><strong>Objective:</strong> This study aims to assess the effects of hyperglycemia on the characteristics of GMSCs in diabetics. <br><strong>Materials and Methods:</strong> 10 patients who consented and fulfilled the criteria for inclusion and exclusion were recruited and categorized as test (HbA1c > 6.5) and control (HbA1c < 6.0). Gingival explants were obtained from gingival collar of teeth, washed, digested and cultured. The cells were subjected to microscopic observation to assess phenotype characteristics, and flow cytometry and qRT-PCR to assess differentiation potential. Stem cell markers CD90, CD73, CD105, CD34, CD45, HLA DR & HLA ABC, osteogenic differentiation markers RUNX2 & OCN, adipogenic differentiation markers PPARG2 & FABP4 and chondrogenic differentiation markers SOX9 & AGCN were evaluated.<br><strong>Results:</strong> Microscopic appearance of spindle shaped cells was found to be comparable in both groups. Flow cytometry results demonstrated comparable expressions with both groups, samples being positive for CD90, CD73, CD105, HLA ABC and negative for CD34, CD45 & HLA DR. There were variations in the expression of markers when assessed for differentiation potentials.<br><strong>Conclusions:</strong> The hyperglycemic environment did not manifest any changes in the phenotypic characteristics of GMSCs among diabetics. However, the expression of certain differentiation markers was significantly altered in the diabetic test population included. Further research is being conducted to understand the GMSCs in a hyperglycemic environment with an aim to develop strategies to optimize its clinical implications. <br><strong>Keywords:</strong> <em>Gingiva; Mesenchymal stem cells; Diabetes mellitus; Cell Differentiation; Hyperglycemia; Flow cytometry.</em></p>2024-03-25T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.006Dental care in patients with periodontal disease and hearing impairment: a scoping review2024-07-09T14:45:17+00:00Carla Mejías-Ampueroivangodoyb@gmail.comMaría León-Vicencioivangodoyb@gmail.comPatricia Melo-Mendietaivangodoyb@gmail.comIván Godoy-Böhmivangodoyb@gmail.com<p><strong>Introduction:</strong> Literature shows that individuals with disabilities, including hearing impairment, often suffer from untreated dental caries, poor oral hygiene, and compromised periodontal health, leading to adverse effects on oral health.<br><strong>Objetive:</strong> This study aims to analyze current evidence concerning dental care strategies for controlling, managing, and preventing biofilm accumulation in patients with hearing impairment.<br><strong>Materials and Methods:</strong> A systematic search was conducted in the databases <em>Scopus, Web of Science, SciELO </em>and <em>PubMed</em> between April and May 2022 to identify articles establishing a relationship between periodontal disease and hearing disability. Full-text articles published in English or Spanish between 2012 and 2022 were included.<br><strong>Results:</strong> Seventeen articles met the inclusion criteria and were analyzed. These included cross-sectional studies, cohort studies, clinical trials, case reports, and case-control studies. Most studies reported fair to poor oral health status among individuals. Nine different interventions or management approaches for treating periodontal disease in patients with hearing impairment were identified.<br><strong>Conclusions:</strong> The current global evidence on the association between periodontal disease and hearing impairment is very limited. Dentists may need to employ various strategies to address communication barriers, as outlined in this study.<br><strong>Keywords:</strong> <em>Periodontal diseases; Hearing loss; Oral health; Clinical protocols; sign language.</em></p>2024-05-09T14:24:21+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.007Association between hyperglycemia and post-exodontia complications in patients with Type II Diabetes Mellitus: A Scoping Review2024-07-09T15:18:24+00:00Ignacio Olivaresignacio.olivares.u@unab.clViviana Arósticaignacio.olivares.u@unab.clAugusto Estayignacio.olivares.u@unab.clRodrigo Quitralignacio.olivares.u@unab.clIgnacio Saninoignacio.olivares.u@unab.cl<p><strong>Introduction:</strong> Diabetes mellitus (DM) is a prevalent chronic metabolic disorder worldwide, with Type II DM (T2DM) emerging as the most widespread variant. In Chile, approximately 11% of adults aged 20 to 79 suffer from this condition. Given its high prevalence, dental surgeons should be trained to evaluate risk factors, particularly the potential complications linked to tooth extraction in individuals with T2DM. <br><strong>Objetive:</strong> To describe the available scientific evidence on post-exodontia complications associated with hyperglycemia in patients with Type II diabetes mellitus. <br><strong>Materials and Methods:</strong> An exploratory systematic review was conducted following the PRISMA-ScR extension protocols using the databases PubMed, EBSCO, Scopus and the Cochrane Library. The search employed the following algorithms: ((<em>“Diabetic patient complications”</em> AND <em>“Dental extractions”</em>)), ((<em>“Diabetes”</em> AND <em>“tooth extraction”</em>)), ((<em>“Glycemia”</em> AND <em>“Tooth extraction complications”</em>), (<strong>(</strong><em>“Blood glucose”</em> AND<em> “Tooth extractions”</em>), ((<em>“Dental extraction sockets”</em> AND<em> “Diabetics”</em>).<br><strong>Results:</strong> Out of a total of 973 articles, 25 were included for this review. Six relevance criteria were considered, revealing safety parameters for conducting extractions in patients with T2DM, with capillary blood glucose levels not exceeding 200 mg/dL for elective extractions and 240 mg/dL for emergency extractions. <br><strong>Conclusions:</strong> There is limited evidence correlating threshold values of hyperglycemia with post-extraction complications in patients with T2DM. Most authors agree that the primary concern is not T2DM itself, but hyperglycemia. Furthermore, there is minimal consistency in the recommended care protocols for these patients.<br><strong>Keywords:</strong> <em>Diabetes mellitus; Tooth extraction; Complications post-exodontia; Surgery, oral; Hyperglycemia; Review.</em></p>2024-05-06T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/joralres.2024.015Effectiveness of Leukocyte- and Platelet-rich Fibrin in the Management of Medication-related Osteonecrosis of the Jaws – A Systematic Review2024-07-25T15:33:14+00:00Rahul Mohandasrahuldas1192@gmail.comSubhashree Mohapatrarahuldas1192@gmail.comMuskaan Singhrahuldas1192@gmail.comSupriya Kheurrahuldas1192@gmail.com<p><strong>Background:</strong> Medication-related osteonecrosis of the jaw (MRONJ) is a rare, but significant adverse event primarily associated with the intake of antiresorptive and antiangiogenic medications. Although antiresorptive and antiangiogenic the-rapies improve life expectancy, particularly in cancer patients, MRONJ may hamper the patient’s quality of life due to pain, discomfort, anxiety, depression, speech impairment, difficulty in swallowing and eating, frequent medical and dental evaluations and treatments, and the possibility of treatment discontinuation. Leukocyte– and Platelet-rich Fibrin (L-PRF) is an autologous platelet aggregate that promotes wound healing by stimulating re-epithelialization, angiogenesis, and extracellular matrix production.<strong> Aim:</strong> The present systematic review aimed to compare the results in the published literature on whether L-PRF is an effective and predictable adjuvant to surgical debridement of necrotic bone for improving the healing efficacy in patients with MRONJ. <br><strong>Materials and Methods:</strong> The <em>PubMed, Scopus, Cochrane, Science Direct, LILACS,</em> and<em> Web of Science</em> databases were searched using the predetermined MeSH terms and eligibility criteria, and the search yielded a total of five articles. Two studies were retrospective, and three studies were case series. <br><strong>Results:</strong> Seventeen participants received a combination of surgical debridement, L-PRF membrane, and antibiotics. Complete wound healing was observed in 70% of the participants, and most of them healed without any complications.<br><strong>Conclusions:</strong> L-PRF as an adjuvant to surgical debridement of necrosed bone appears to have a positive association with the healing outcome in patients with MRONJ.<br><strong>Keywords:</strong> <em>Jaw; Osteonecrosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Wound healing; Guided tissue regeneration; Platelet-rich Fibrin.</em></p>2024-07-17T00:00:00+00:00##submission.copyrightStatement##https://joralres.com/ojs-3.1.0/index.php/JOralRes/article/view/1597Ceramic facet as an alternative to replacing a implant-supported crown in infraocclusion - clinical case2024-10-22T14:41:36+00:00Natalia Marcusnmarcus@clinicazenit.clFernando Grandónnmarcus@clinicazenit.clMichael Wendlernmarcus@clinicazenit.clPaulina Péreznmarcus@clinicazenit.clDaniela Pinonmarcus@clinicazenit.cl<p><strong>Introduction:</strong> Scientific evidence has shown us that dental implants do not adapt to the natural eruptive process of the teeth, so over the years they can stand in infraposition in relation to the neighboring teeth, especially when the implants have been placed in patients at the age of growth.<br><strong>Case Report:</strong> In this case report, an alternative is considered to avoid removing the implant-supported crown and having to make a new one by adhering a lithium disilicate veneer. The application of hydrofluoric acid and silane is considered the gold standard for the conditioning of glass ceramics, but it presents high toxicity and is a protocol-sensitive method. <br><strong>Conclusion:</strong> The objective is to propose an alternative for the preparation and conditioning of ceramics based on ammonium polyflouride under absolute isolation. This approach involves returning the patient´s function and aesthetics with a conservative and economical treatment compared to total replacement of the prosthesis.<br><strong>Keywords:</strong><em> Dental veneers; Ceramic; Ammonium poly-fluoride; Dental esthetics; Dental implants; Hydrofluoride acid.</em></p>2024-09-30T00:00:00+00:00##submission.copyrightStatement##